Selected evidence
A curated starting point for current and foundational research on MMP-7, biliary atresia, emerging diagnostic approaches, and clinical evaluation.
This is a selected educational bibliography—not a systematic review, endorsement, or clinical protocol. Follow the linked record for the full abstract, methods, limitations, disclosures, and publication status. Last reviewed September 22, 2026.
Chi S, et al. Hepatology Communications. Prospective evaluation across five tertiary centers in infants younger than six months with persistent jaundice.
Multicenter studyStetson A, et al. Advances in Pediatrics. Review of earlier recognition, direct bilirubin testing, imaging, emerging biomarkers, and timely intervention.
ReviewSimões BCB, et al. Pediatric Surgery International. Retrospective study of serum GGT and ultrasonographic parameters in infants evaluated for biliary atresia.
Diagnostic studyLi Z, Deng Y, Liao Q. BMC Pediatrics. Synthesis of diagnostic-accuracy evidence and sources of variation across published studies.
Systematic reviewKong F, et al. Hepatology Research. Mechanistic work examining cholangiocyte expression, downstream signaling, and fibrosis associations.
Mechanistic studyPandurangi S, et al. Hepatology. Large North American cohort evaluating serum MMP-7 with two assay platforms.
Validation cohortJournal of Translational Medicine. Diagnostic-accuracy study with internal and external validation cohorts.
Validation studyTam PKH, Wells RG, Tang CSM, et al. Nature Reviews Disease Primers. Broad review of disease biology, epidemiology, diagnosis, treatment, and quality of life.
Disease primerJiang J, et al. Pediatrics. Evaluation of serum MMP-7 in infants with biliary atresia and comparison groups.
Foundational studyYang L, et al. Hepatology. Foundational diagnostic-accuracy study that helped establish MMP-7 as a candidate serum biomarker.
Foundational studyFawaz R, et al. Joint NASPGHAN–ESPGHAN recommendations addressing recognition and evaluation of infant cholestasis.
Clinical guidelineBecause the field changes, use a live literature search for work published after our review date.