Families and caregivers
Understand persistent jaundice, pale stools, dark urine, evaluation, and why prompt medical attention matters.
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Education · Research · Collaboration
Advancing knowledge and access around MMP-7
Dx4Liver advances education, research awareness, and institutional collaboration focused on MMP-7 measurement and biliary atresia.
- Science made understandable
- Audience-specific information
- Institutional collaboration
Start with what matters
Clear paths for every audience
Biliary atresia moves quickly. Good information should, too. Choose the path that fits your needs.
Clinicians and researchers
Review the evolving evidence for serum MMP-7 as one component of a complete biliary atresia evaluation.
View clinical educationHospitals and laboratories
Learn about TR-FRET measurement principles, institutional responsibilities, and how to contact Dx4Liver.
View laboratory informationUnderstanding biliary atresia
Earlier recognition supports faster specialist evaluation
Biliary atresia is a rare disease of infancy in which bile ducts become injured and obstructed. Persistent jaundice, pale or clay-colored stools, and dark urine need prompt medical evaluation.
MMP-7 is one of several tools being studied and used to support evaluation. No single biomarker replaces the complete clinical workup or establishes the final diagnosis by itself.
Measurement technology
TR-FRET: a streamlined fluorescence approach
Time-resolved fluorescence resonance energy transfer is a homogeneous, plate-based technology used for quantitative biomarker measurement.
Its proximity-based donor and acceptor system supports sensitive fluorescence detection with reduced background and a no-wash workflow. Assay performance and appropriate use must be established by each laboratory.
See how TR-FRET worksEvidence library
Follow the evolving science
Explore selected peer-reviewed publications covering MMP-7, biliary atresia, emerging diagnostic approaches, and clinical guidance.
2026 multicenter study
A rapid point-of-care MMP-7 assay was evaluated across five tertiary centers.
2025 meta-analysis
A systematic review synthesized evidence on the diagnostic accuracy of MMP-7.
2024 North American cohort
A large cohort evaluated serum MMP-7 using two assay platforms.
Institutional inquiries
Interested in MMP-7 measurement?
Qualified hospitals and laboratories may contact Dx4Liver for general institutional information about MMP-7 measurement and TR-FRET technology.